Last most-relevant publications
- The Origins and the Biological Consequences of the Pur/Pyr DNA·RNA Asymmetry Chem
- Oncogenic mutations at the EGFR ectodomain structurally converge to remove a steric hindrance on a kinase-coupled cryptic epitope Proceedings of the National Academy of Sciences
- An In-Depth Look at DNA Crystals through the Prism of Molecular Dynamics Simulations Chem
- Predicting the limit of intramolecular H-Bonding with classical molecular dynamics Angewandte Chemie International Edition
A study by the scientists Xavier Salvatella and Modesto Orozco at IRB Barcelona reveals the existence of information highways that connect and correlate distant sites within a single protein.
Published in Nature Communications, the article furthers a key theoretical field for drug discovery, as it would allow the discovery of many more drug binding sites in proteins of biomedical interest.