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nucleR is a R/Bioconductor package for working with tiling arrays and next generation sequencing. It uses a novel aproach in this field which comprises a deep profile cleaning using Fourier Transform and peak scoring for a quick and flexible nucleosome calling. More information is available in the article:

Oscar Flores and Modesto Orozco (2011). nucleR: a package for non-parametric nucleosome positioning. Bioinformatics 2011, doi:10.1093/bioinformatics/btr345

Download and Installation

Most updated nucleR code and manual are available in the Bioconductor repository. This is included in the release version of Bioconductor since v.2.10.

download_imageGo to Bioconductor webpage

Once nucleR is installed, you can check its main functions by executing the example workflow:

> library(nucleR)
> example(nucleR)