Large scale data management for genomics projects

We are involved in a series of large scale biomedical and biotechnogical genomics projects, characterized by the need of manage large amounts of data. We provide data storage, mechanism for data transmission to project partners, and distribution of public data results. Advanced database both relational and noSql based ae available. Also we are adapting bioinformatics algorithms to large scale calculations compatible with the HPC environment.

Relevant projects

• Sequencing and analysis of Chronic Lynphocytic Leukemia, part of the Inernational Cancer Genome Consortium
• Pan-Cancer project for comprehensive cross-tumor analysis
• A BLUEPRINT of Haematopoietic Epigenomes
• TransPlant. European transNational infrastructure for plant genomics
• IMID-Kit

Relevant publications

• Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia., Puente, Xose S., Pinyol Magda, Quesada Víctor, Conde Laura, Ordóñez Gonzalo R., Villamor Neus, Escaramis Georgia, Jares Pedro, Beà Sílvia, González-Díaz Marcos, et al. , Nature, 2011 Jul 7, Volume 475, Issue 7354, p.101-5, (2011)

• Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia., Quesada, Víctor, Conde Laura, Villamor Neus, Ordóñez Gonzalo R., Jares Pedro, Bassaganyas Laia, Ramsay Andrew J., Beà Sílvia, Pinyol Magda, Martínez-Trillos Alejandra, et al. , Nat Genet, 2012 Jan, Volume 44, Issue 1, p.47-52, (2012)
• Risk variants for psoriasis vulgaris in a large case-control collection and association with clinical subphenotypes., Julià, Antonio, Tortosa Raül, Hernanz José Manuel, Cañete Juan D., Fonseca Eduardo, Ferrándiz Carlos, Unamuno Pablo, Puig Lluís, Fernández-Sueiro José Luís, Sanmartí Raimon, et al. , Hum Mol Genet, 2012 Oct 15, Volume 21, Issue 20, p.4549-57, (2012)
• A genome-wide association study on a southern European population identifies a new Crohn's disease susceptibility locus at RBX1-EP300., Julià, Antonio, Domènech Eugeni, Ricart Elena, Tortosa Raül, García-Sánchez Valle, Gisbert Javier P., Mateu Pilar Nos, Gutiérrez Ana, Gomollón Fernando, Mendoza Juan Luís, et al. , Gut, 2013 Oct, Volume 62, Issue 10, p.1440-5, (2013)
• A genome-wide association study identifies a novel locus at 6q22.1 associated with ulcerative colitis., Julià, Antonio, Domènech Eugeni, Chaparro María, García-Sánchez Valle, Gomollón Fernando, Panés Julián, Mañosa Míriam, de Acosta Manuel Barreiro-, Gutiérrez Ana, Garcia-Planella Esther, et al. , Hum Mol Genet, 2014 Jul 31, (2014)